Vitamin D Reduced Non-Vertebral Bone Fractures by 29%

$Vitamin D reduced bone fractures$

Study Title: "Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials."

Number of Participants: 33,265

Length of Study: Meta-analysis of 12 double-blind randomized controlled trials (RCTs) for non-vertebral fractures and 8 randomized controlled trials for hip fractures

Type of Study: Meta-Analysis

Publication: Archives of Internal Medicine

Study Result: In those individuals taking more than 400 IU of Vitamin D a day, there was a 29% decrease for non-vertebral fractures in the aged 65+ group not living in an institution. There was a 20% decrease in non-vertebral bone fractures and a 18% decrease in hip fractures for the 400+ IU/day in the overall Vitamin D group, independent of calcium supplementation.

In this large meta-analysis of 12 double-blind randomized controlled trials (RCTs) for non-vertebral fractures and 8 randomized controlled trials for hip fractures, it was found that 400+ IU/day of Vitamin D resulted in a 29% decrease in non-vertebral bone fractures for the aged 65+ subgroup not living in an institution. There was an overall 20% decrease for non-vertebral fractures in all subgroups and a 18% decrease in hip fractures.

The study authors concluded:

“Nonvertebral fracture prevention with vitamin D is dose dependent, and a higher dose should reduce fractures by at least 20% for individuals aged 65 years or older.”

See Study on PubMed >

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