244 patients were given 180 micrograms of Vitamin K2, as menaquinone-7 (MK-7). They were followed for three years to determine the Bone Mineral Density of the lumbar spine, total hip, and femoral neck. It was found that there were fewer bone fractures in the MK-7 group compared to placebo. MK-7 intake significantly improved vitamin K status and decreased the age-related decline in Bone Mineral Density at the lumbar spine and femoral neck, but not at the total hip. Bone strength was also favorably affected by MK-7. MK-7 significantly decreased the loss in vertebral height of the lower thoracic region at the mid-site of the vertebrae.
MK-7 (Vitamin K2) Reduced Bone Loss in Postmenopausal Women
Study Title: "Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women."
Number of Participants: 244
Length of Study: 36 months
Type of Study: Double Blind study
Publication: Osteoporosis International
Study Result: MK-7 intake significantly improved vitamin K status and decreased the age-related decline in Bone Mineral Density at the lumbar spine and femoral neck. There were less fractures in the MK-7 group. Bone strength was also favorably affected by MK-7.
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