In some countries extracts of the plant Hypericum perforatum L. (popularly called St. John's wort) are widely used for treating patients with depressive symptoms. To investigate whether extracts of hypericum are more effective than placebo and as effective as standard…
99 patients suffering from therapy-resistant depression, meaning they did not improve when previously taking anti-depressant drugs or electroconvulsive therapy, were given 5-HTP at an average of 200 mg per day combined with the peripheral decarboxylase inhibitor, carbidopa. Complete recovery was…
In 1991, 5-HTP was compared to the SSRI fluvoxamine (Luvox) for effectiveness against depression. Fluvoxamine is comparable to other SSRIs, such as Prozac, Zoloft and Paxil. In the study, 36 patients received either 300 mg daily of 5-HTP or 150…
The effectiveness of 5-HTP as an antidepressant drug was studied with 59 patients with depressive symptoms using the Rating Scale for Depression. In this double-blind clinical study of 5-HTP treatment of depression, a daily dose of 150 - 300 mg…
