Eighty men and women with high cholesterol were given a Bergamot-derived extract for 6 months. There was a 20% reduction in LDL, the unhealthy fraction of cholesterol; there was also a 17% decrease in triglycerides. There was a small increase in HDL, the healthy cholesterol fraction. Researchers also scanned the carotid artery to see if Bergamot improved artery healthy by reducing the plaque buildup in the artery. There was a 25% reduction in artery plaque.