Seventy-seven patients with elevated LDL cholesterol and triglycerides were randomly assigned to a control group receiving placebo, two groups receiving orally administered rosuvastatin, a group receiving Bergamot alone orally (1000 mg/daily) and a group receiving Bergamot (1000 mg/daily) plus rosuvastatin (10mg/daily). The group receiving Bergamot experienced a 41% decrease in LDL cholesterol and a 31% decrease in triglycerides. HDL cholesterol had a favorable increase of 18%. Other favorable results were found in biomarkers for heart disease, suggesting Bergamot as a powerful therapeutic agent against heart disease.
Bergamot Significantly Reduces LDL Cholesterol by 41%
Study Title: "Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia"
Number of Participants: 77
Length of Study: 30 days
Type of Study: Prospective, open-label, parallel group, placebo-controlled study
Publication: International Journal of Cardiology
Study Result: LDL cholesterol reduced by 41%, HDL cholesterol increased by 18%, triglycerides reduced by 31% and other heart disease biomarkers improved
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